Code is covered without prior authorization (high confidence)
Documentation Required
Medical record must include a detailed clinical history and exposure history.
Medical record must include a documented differential diagnosis justifying the targets ordered and how results will affect management.
Documentation of patient signs/symptoms and clinical correlation with NAAT results to justify treatment decisions (e.g., antibiotic therapy).
When viability or pathogenicity is uncertain, documentation of consideration for confirmatory testing (e.g., culture, additional assays) or rationale for not performing such testing.
Key Coverage Criteria
Acute diarrhea with moderate-to-severe symptoms (e.g., fever, bloody or mucoid stools, dysentery, severe dehydration, severe abdominal pain).
Community-acquired diarrhea that persists for more than seven days.
Travel-associated diarrhea of uncertain etiology.
Individuals with signs and symptoms of gastroenteritis or infectious colitis (specified as the clinical indication for CPT 87507).
Immunocompromised individuals (e.g., HIV, receiving chemotherapy or systemic steroids) presenting with acute diarrhea.
Use of GI panels (CPT 87505, 87506, 87507) to detect bacterial, viral, or parasitic nucleic acid in stool from patients with signs/symptoms suggesting paralytic ileus with persistent abdominal pain ≤24 hours plus either fever or nausea/vomiting.