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Intravenous Immune Globulin - Policy Article
A52509
Noridian Healthcare Solutions, LLC (J19)
Effective: January 1, 2025
Updated: December 31, 2025
Policy Summary
IVIG administered in the home for primary immunodeficiency is covered when the product is an approved pooled plasma derivative, the patient has a documented diagnosis of primary immunodeficiency, and the treating practitioner documents that home administration is medically appropriate. Coverage and payment require compliance with Final Rule 1713 face-to-face and WOPD requirements where applicable, correct billing of HCPCS Q2052 (one paid unit per infusion date) and proper application of JW/JZ modifiers per the stated scenarios and effective dates.
Coverage Criteria Preview
Key requirements from the full policy
"IVIG is covered when the product is an approved pooled plasma derivative indicated for treatment of primary immunodeficiency disease."
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