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Billing and Coding: Amniotic Membrane Billing Guidelines for HCPCS Code V2790
A53441
Effective: October 3, 2019
Updated: December 31, 2025
Policy Summary
HCPCS V2790 (amniotic membrane) is bundled and included in payment for CPT 65778 and 65779 and is included in inpatient OPPS and ASC facility allowances, so it generally should not be billed separately to Part B. The only allowed separate reimbursement is in the office setting when billed with CPT 65780 if an invoice is submitted (fax for electronic claims, paper invoice for paper claims). V2790 should not be billed with CPT 65775 unless CPT 65778 or 65779 are added to account for membrane application as specified.
Coverage Criteria Preview
Key requirements from the full policy
"HCPCS V2790 is bundled and included in the allowance when billed with CPT 65778."
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