Billing and Coding: MolDX: HTTLPR Gene Testing

HTTLPR (serotonin transporter) genotyping (CPT 81479) is statutorily excluded and not covered for dates of service on or after June 26, 2013 due to insufficient evidence of clinical utility. Claims seeking an HTTLPR analysis denial should include CPT 81479 and the DEX Z‑Code in the specified claim fields; ABNs are not required for statutorily excluded services, though voluntary ABNs should use modifier GX and documented ABNs use modifier GY.

"HTTLPR (serotonin transporter) gene testing is statutorily excluded and not covered for dates of service on or after 2013-06-26."

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