Billing and Coding: MolDX: Oncotype DX® Colon Cancer

The Oncotype DX Colon Cancer Assay is used to predict recurrence risk for patients with Stage II colon cancer. Billing requires entering 1 unit of service, selecting an appropriate ICD-10-CM diagnosis code, and including the DEX Z‑Code adjacent to the CPT code in specified Part A (SV202-7/Block 80) or Part B (Loop 2400/SV101-7/Item 19) claim fields. The policy provides billing/coding instructions but does not state clinical coverage exclusions or frequency beyond the single UOS billing instruction.

"Oncotype DX Colon Cancer Assay is intended to predict recurrence risk for patients with Stage II colon cancer."

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