Billing and Coding: Coverage of Intravenous Immune Globulin for Treatment of Primary Immune Deficiency Diseases in the Home – Medicare Benefit Policy Manual, Chapter 15, 50.6

Medicare covers intravenous immune globulin (IVIG) administered in the patient's home for treatment of a diagnosed primary immune deficiency disease when the treating physician determines home administration is medically appropriate and the product is an approved pooled plasma derivative. The home infusion benefit excludes coverage for administration-related items and services; local coverage determinations (e.g., Noridian LCD) may impose additional indications, documentation, or frequency limits.

"IVIG is covered when the patient has a diagnosed primary immune deficiency disease."

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