ArticleActive
Billing and Coding: Coverage of Intravenous Immune Globulin for Treatment of Primary Immune Deficiency Diseases in the Home Medicare Benefit Policy Manual, Chapter 15, 50.6
A54662
Effective: August 13, 2019
Updated: December 31, 2025
Policy Summary
Medicare covers intravenous immune globulin (IVIG) administered in the patient’s home for the treatment of diagnosed primary immune deficiency diseases when the IVIG is an approved pooled plasma derivative and the physician documents that home administration is medically appropriate. The benefit excludes coverage for items and services related to administration (e.g., administration supplies or services) and does not require use of durable medical equipment; check applicable local coverage determinations for additional indications or requirements.
Coverage Criteria Preview
Key requirements from the full policy
"Patient has a diagnosed primary immune deficiency disease (PID) and IVIG is being used for treatment of that PID."
Sign up to see full coverage criteria, indications, and limitations.