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Billing and Coding: MolDX: BluePrint® Test
A55146
Wisconsin Physicians Service Insurance Corporation (J05)
Effective: October 30, 2025
Updated: December 31, 2025
Policy Summary
The MolDX assessment found insufficient evidence of clinical utility for the BluePrint® molecular subtyping assay, making it statutorily excluded and not covered by Medicare. To obtain a denial, submit the service as CPT 81479 and indicate statutory exclusion by appending modifier GY (use GX only for a voluntary ABN); include the DEX Z-Code identifier adjacent to the CPT code in the specified Part A and Part B claim fields.
Coverage Criteria Preview
Key requirements from the full policy
"The BluePrint® molecular subtyping assay is statutorily excluded from Medicare coverage and is not a covered service due to insufficient evidence of clinical utility."
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