Billing and Coding: MolDX: HTTLPR Gene Testing

HTTLPR (serotonin transporter) genotyping is statutorily excluded and not covered due to insufficient and conflicting evidence. To obtain a denial, submit claims with CPT 81479 and follow claim filing instructions: ABN guidance (GX for voluntary ABN, GY to indicate ABN on file) and include the DEX Z-Code adjacent to the CPT code in the specified Part A and Part B claim fields.

"HTTLPR (serotonin transporter) genotyping testing is a statutorily excluded service and is not covered by Medicare/Medicaid."

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