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Billing and Coding: Intraarticular Knee Injections of Hyaluronan
A56157
Wisconsin Physicians Service Insurance Corporation (J05)
Effective: August 1, 2024
Updated: December 31, 2025
Policy Summary
Medicare covers intraarticular hyaluronan (viscosupplementation) for symptomatic osteoarthritis of the knee when the patient has failed at least 3 months of conservative therapy and radiographic evidence supports the diagnosis. Dosing and frequency must follow the FDA-approved package insert for the specific HCPCS-coded product, documentation of prior benefit is required for repeat series (minimum 6-month interval), and billing must follow modifiers and units rules (EJ for subsequent injections in a series, JW for discarded drug, appropriate RT/LT or -50 modifiers).
Coverage Criteria Preview
Key requirements from the full policy
"Intraarticular hyaluronan is covered for treatment of symptomatic osteoarthritis of the knee in patients who have failed to respond adequately for at least 3 months to simple analgesics and conserv..."
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