ArticleActive
Billing and Coding: MolDX: MGMT Promoter Methylation Analysis
A56983
Effective: August 22, 2024
Updated: December 31, 2025
Policy Summary
This billing/coding guideline requires MGMT Promoter Methylation Analysis to be reported with CPT 81287 and the appropriate DEX Z-Code identifier. Claims must use Bill Type 022x for Skilled Nursing Inpatient (Medicare Part B), include 1 unit of service, and place the DEX Z-Code in the specified electronic or paper claim fields; an appropriate ICD-10-CM diagnosis code must also be included.
Coverage Criteria Preview
Key requirements from the full policy
"Report MGMT Promoter Methylation Analysis using CPT code 81287 adjacent to the appropriate DEX Z-Code identifier."
Sign up to see full coverage criteria, indications, and limitations.