Billing and Coding: MolDX: EndoPredict Breast Cancer Gene Expression Test

Billing for the EndoPredict breast cancer gene expression test requires reporting CPT 81522 with one unit of service and including the appropriate DEX Z‑Code adjacent to the CPT code in the claim narrative. For Part B use Loop 2400/SV101-7 (837P) or Box 19 (paper); for Part A use Line SV202-7 (837I) or UB04 Block 80, and include the appropriate ICD-10-CM diagnosis code. These are billing/coding instructions that complement LCD L37356.

"Report EndoPredict using CPT code 81522 and enter 1 unit of service (UOS)."

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