Billing and Coding: Multimarker Serum Tests Related to Ovarian Cancer Testing

This billing and coding article provides Medicare billing requirements and coding guidance for multimarker serum tests related to ovarian cancer testing; it references specific CPT codes (81500 for ROMA, 81503 for OVA1, 0003U for OVERA). Claims must include a valid ICD-10-CM diagnosis that best describes the condition, and when applicable must report the referring/ordering physician's name and NPI; providers should also review NCCI and OPPS edits before billing.

"Multimarker serum tests related to the evaluation or monitoring of ovarian cancer may be billed under this policy in accordance with the applicable Local Coverage Determination (LCD)."

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