Billing and Coding: MolDX: Signatera and Minimal Residual Disease Testing for Colorectal Cancer

This billing/coding guidance for Signatera MRD testing for colorectal cancer requires selecting the appropriate CPT and ICD-10-CM codes, reporting 1 unit of service per claim, and including the DEX Z-Code adjacent to the CPT code in specified Part A and Part B claim fields. Coverage and billing must follow the referenced LCD DL38305.

"The billed service is Signatera minimal residual disease (MRD) testing specifically for colorectal cancer."

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