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Billing and Coding: MolDX: Melanoma Risk Stratification Molecular Testing
A57290
Effective: October 1, 2025
Updated: December 31, 2025
Policy Summary
Claims for MolDX melanoma risk stratification molecular testing must include the appropriate CPT code, a single unit of service (UOS = 1), the correct ICD-10-CM code, and the DEX Z-Code entered adjacent to the CPT line in specified Part A or Part B fields. DEX Z-Code placement differs by claim type (Part B: Loop 2400 or SV101-7 for 837P / Item 19 for paper; Part A: SV202-7 for 837I / Block 80 for UB04) and no additional characters may be added on the SV101-7 line.
Coverage Criteria Preview
Key requirements from the full policy
"Select and report the appropriate CPT code for the melanoma risk stratification molecular diagnostic service."
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