Billing and Coding: MolDX: MGMT Promoter Methylation Analysis

This policy provides billing and coding instructions for reporting MGMT Promoter Methylation Analysis (CPT 81287), including required claim elements such as Bill Type Code 022x for Skilled Nursing Inpatient (Medicare Part B), entry of 1 unit of service, and placement of the appropriate DEX Z-Code adjacent to the CPT code on specified electronic and paper claim fields. Claimants must also report an appropriate ICD-10-CM diagnosis code and follow the Local Coverage Determination for coverage and medical necessity decisions.

"Bill Type Code 022x guidance applies to Skilled Nursing – Inpatient claims under Medicare Part B only."

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