ArticleActive
Billing and Coding: MolDX: MGMT Promoter Methylation Analysis
A57433
Effective: October 14, 2021
Updated: December 31, 2025
Policy Summary
This billing/coding guidance requires MGMT Promoter Methylation Analysis to be reported with CPT 81287, with one unit of service and the appropriate ICD-10-CM diagnosis code. Place the DEX Z-Code identifier adjacent to the CPT code on the claim (Part B: Loop 2400/SV101-7 for electronic 837P or Item 19 for paper; Part A: SV202-7 for 837I or UB04 Block 80) and use Bill Type Code 022x for skilled nursing inpatient under Medicare Part B. Coverage determinations remain subject to the applicable LCD; this article describes claim submission requirements only.
Coverage Criteria Preview
Key requirements from the full policy
"Bill Type Code 022x applies to Skilled Nursing - Inpatient and is limited to Medicare Part B claim submission."
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