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Billing and Coding: MolDX: Oncotype DX® Breast Cancer for DCIS (Genomic Health)
A57583
Wisconsin Physicians Service Insurance Corporation (J05)
Effective: October 30, 2025
Updated: December 31, 2025
Policy Summary
This billing/coding guideline requires reporting Oncotype DX Breast Cancer for DCIS with PLA code 0045U and one unit of service, including the appropriate DEX Z-Code adjacent to the CPT code. It specifies exact claim fields for Part B (Loop 2400/SV101-7 for 837P; Box 19 for paper) and Part A (Line SV202-7 for 837I; Block 80 for UB04) submissions and requires selection of the correct ICD-10-CM diagnosis code.
Coverage Criteria Preview
Key requirements from the full policy
"Report Oncotype DX Breast Cancer for DCIS using PLA code 0045U."
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