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Billing and Coding: MolDX: Oncotype DX® Breast Cancer for DCIS (Genomic Health)
A57620
Effective: November 25, 2021
Updated: December 31, 2025
Policy Summary
This billing and coding guideline specifies submission requirements for the Oncotype DX Breast Cancer for DCIS test: use PLA code 0045U and report 1 unit of service. Include the appropriate DEX Z‑Code adjacent to the CPT code in the specified claim fields depending on claim type and format (Part A vs Part B, 837P/837I electronic vs paper/UB04), and report the supporting ICD-10-CM diagnosis code.
Coverage Criteria Preview
Key requirements from the full policy
"Report the Oncotype DX Breast Cancer for DCIS service using PLA code 0045U on the claim."
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