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Billing and Coding: MolDX: Next-Generation Sequencing for Solid Tumors
A57901
Effective: April 1, 2025
Updated: December 31, 2025
Policy Summary
This billing and coding guidance requires reporting the appropriate CPT and ICD-10-CM codes and entering one unit of service (UOS=1) for Next-Generation Sequencing for Solid Tumors. The DEX Z-Code identifier must be included adjacent to the CPT code in specified comment/narrative fields depending on claim type (Part B: Loop 2400/SV101-7/Item 19; Part A: SV202-7/Block 80) and no additional characters may be added to the SV101-7 entry.
Coverage Criteria Preview
Key requirements from the full policy
"When entering the DEX Z-Code on the SV101-7 field for Part B claims, do not add additional characters or other information on that line."
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