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Response to Comments: Off-label Use of Rituximab and Rituximab Biosimilars
A58727
Effective: June 24, 2021
Updated: December 31, 2025
Policy Summary
This response document (Policy A58727) concerns off-label use of rituximab and rituximab biosimilars for non-anti-neoplastic (non-oncologic) conditions and summarizes comments received during the public comment period. The excerpt provided does not include specific clinical coverage criteria, limitations, documentation requirements, or frequency limits; review of the full policy (DL38920) is required to extract actionable coverage rules.
Coverage Criteria Preview
Key requirements from the full policy
"This policy addresses off-label use of rituximab and rituximab biosimilars for non-anti-neoplastic (non-oncologic) conditions and applies to such uses."
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