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Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasia
A59015
Effective: May 14, 2023
Updated: December 31, 2025
Policy Summary
This billing and coding guidance specifies required claim fields for molecular testing for detection of upper gastrointestinal metaplasia, dysplasia, and neoplasia: report the correct CPT and ICD-10-CM codes, enter 1 unit of service, and include the appropriate DEX Z‑Code adjacent to the CPT. DEX Z‑Code placement differs by claim type: for Part B use Loop 2400/SV101-7 (837P) or Box 19 (paper); for Part A use SV202-7 (837I) or UB04 Block 80. These elements are required on claims to support processing and to avoid denials.
Coverage Criteria Preview
Key requirements from the full policy
"Select and report the appropriate CPT code for the molecular test being billed."
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