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Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasia
A59051
Effective: February 13, 2025
Updated: December 31, 2025
Policy Summary
This billing and coding guideline specifies required claim elements for MolDX molecular testing for detection of upper gastrointestinal metaplasia, dysplasia, and neoplasia. Claims must report the appropriate CPT and ICD-10-CM codes, include exactly 1 unit of service, and include the DEX Z-Code adjacent to the CPT code in the designated electronic or paper claim fields (Part A and Part B) to avoid denial.
Coverage Criteria Preview
Key requirements from the full policy
"Claims that do not include the required DEX Z-Code identifier adjacent to the CPT code, the appropriate CPT code, and the appropriate ICD-10-CM code may be denied."
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