Billing and Coding: Luteinizing Hormone-Releasing Hormone (LHRH) Analogs

Coverage of LHRH analog administration requires prescribing, dosing, and administration to conform to FDA-approved labeling and applicable LCD L39387 billing rules. The JW modifier must be used for discarded Part B single‑use vial/package drugs (document the discarded amount in the medical record), except for drugs provided under the Competitive Acquisition Program (CAP); specified administration CPT codes may be billed only with the listed HCPCS drug codes.

"Administration of LHRH analogs is covered when prescribed, dosed, and administered consistent with FDA-approved labeling."

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