Billing and Coding: High Resolution Anoscopy

High-resolution anoscopy (HRA) is indicated for patients with abnormal findings on anoscopy or digital rectal examination, for patients with abnormal anorectal cytology, and for patients with a history of HPV-related anal disease or anal squamous dysplasia; CPT codes 46601 and 46607 should be used for these scenarios. The policy does not state coverage for routine screening of asymptomatic individuals or specify frequency limits, and documentation of the abnormal exam/cytology or prior HPV-related disease should be included in the medical record. Populations at increased risk (e.g., MSM and immunocompromised individuals) are noted in the description but explicit coverage criteria for screening these groups is not specified and may require manual clarification.

"High-resolution anoscopy (HRA) is covered for patients with abnormalities detected on anoscopy."

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