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Billing and Coding: Skin Substitutes Grafts/Cellular and Tissue-Based Products for the Treatment of Diabetic Foot Ulcers and Venous Leg Ulcers
A59628
Updated: December 6, 2025
See LCD L39764Policy Summary
Covers application of skin substitute grafts (non‑autologous human, xenograft, cellular/acellular and sheet-forming biological products) for diabetic foot and venous leg ulcers when meeting LCD L39764 reasonable-and-necessary criteria, and excludes non‑graft wound dressings and injected skin substitutes as separately billable (these are bundled/not payable). Key requirements: follow the LCD for medical necessity, do not report graft application codes with non‑graft or injected products, and use the appropriate Medicare modifier (GA/GX/GY/GZ) when billing non‑covered services.
Covered Medical Codes
This policy references 280 medical codes
238
HCPCS
42
ICD-10-CM