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Billing and Coding: MolDX: Molecular Testing for Identification and Management of Hereditary Transthyretin Amyloidosis
A59848
Updated: December 31, 2025
Policy Summary
Billing for molecular testing for hereditary transthyretin (TTR) amyloidosis requires selection of the appropriate CPT and ICD-10-CM codes, reporting one unit of service, and limiting billing to one test per patient. The DEX Z-Code identifier must be entered adjacent to the CPT code in the specified claim fields for Part A and Part B (Loop 2400/SV101-7 or Box 19 for Part B; SV202-7 or Block 80 for Part A), and no extra characters may be added on the SV101-7 line.
Coverage Criteria Preview
Key requirements from the full policy
"Only one molecular test for hereditary transthyretin (TTR) amyloidosis may be billed per patient."
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