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Billing and Coding: MolDX: Non-Next Generation Sequencing Tests for the Diagnosis of BCR-ABL Negative Myeloproliferative Neoplasms
A59939
Wisconsin Physicians Service Insurance Corporation (J05)
Effective: November 20, 2025
Updated: December 31, 2025
See LCD L38176Policy Summary
Billing for non-NGS tests to diagnose BCR-ABL negative myeloproliferative neoplasms allows sequential single-gene (non-NGS) testing when LCD DL40022 criteria are met, but multi-gene panels (NGS or otherwise) must be billed as a single panel unit and cannot be unbundled. Each CPT/PLA code listed is limited to one unit of service per lifetime per diagnosis; claims must include the appropriate CPT/PLA code, 1 UOS, DEX Z-Code in the specified claim field(s), and an appropriate ICD-10-CM code, and NGS testing must comply with referenced NGS policies (L38176/A57878).
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"Single-gene (non-NGS) testing (e."
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