Payer PolicyActive
Cancer Vaccines
AETNA-CPB-0557
Aetna
Effective: August 10, 2023
Updated: December 6, 2025
created · Dec 2, 2025
Policy Summary
Aetna considers the listed cancer vaccines experimental and investigational and not covered—specifically: helper multi‑peptide (6MHP) for metastatic melanoma; HLA‑A24‑binding peptide vaccines for gastric cancer; melanoma/Theraccine/Oncophage vaccine for any indication; p16(INK4a)‑based peptide vaccines for HPV‑associated cancers; and p62 DNA vaccine (Elenagen) for solid tumors—because safety and effectiveness have not been established.
Coverage Criteria Preview
Key requirements from the full policy
"None explicitly covered. The policy identifies cancer vaccines and listed vaccine therapies as experimental and investigational and therefore not established as safe and effective for the indicatio..."
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