Payer PolicyActive
Convection-Enhanced Intraparenchymal Delivery of Drugs to the Brain
AETNA-CPB-0731
Aetna
Effective: September 22, 2023
Updated: December 6, 2025
created · Dec 2, 2025
Policy Summary
Aetna considers convection-enhanced intraparenchymal delivery of drugs to the brain experimental/investigational and does not cover it for any indications, including primary brain malignancies (C71.0–C71.9), secondary brain neoplasms (C79.31, C79.49), Alzheimer’s disease (G30.0–G30.9), or epilepsy (G40.001–G40.909). Coverage is excluded because safety and effectiveness have not been established, and no approved clinical indications or coverage requirements are provided.
Coverage Criteria Preview
Key requirements from the full policy
"None — Aetna considers convection-enhanced delivery of drugs into brain parenchyma experimental and investigational because the safety and effectiveness of this approach has not been established."
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