Epiretinal Radiation Therapy

Epiretinal/epimacular radiation therapy (including Epi‑Rad90 and epi‑macular brachytherapy) is considered experimental/investigational and not covered for age‑related macular degeneration (ICD‑10 H35.30–H35.389) or any other indication. Key requirement: Aetna cites insufficient and inconsistent evidence (randomized trials such as CABERNET failed to show noninferiority/superiority and showed higher serious adverse events) and reported harms (retinal tear/detachment, hemorrhage, cataract progression, radiation retinopathy), so routine use is not supported.

"None — Aetna considers epiretinal radiation therapy experimental and investigational for the treatment of age-related macular degeneration (AMD) or any other conditions because there is insufficien..."

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