Oral Screening and Lesion Identification Systems

Aetna does not describe coverage for adjunctive oral screening devices, salivary tests, or imaging systems — conventional visual and tactile oral examination with histopathologic assessment (biopsy) remains the clinical standard. Epstein‑Barr virus testing, oral HPV testing (e.g., OraRisk), salivary biomarkers (DUSP100, IL‑1B, IL‑8, MMP‑9, microRNA, mRNA, s100P, TNF‑alpha), salivary hypermethylated DNA, and salivary metabolite biomarkers are considered experimental/investigational and not covered because their effectiveness has not been established.

"No specific "Covered Indications" section is provided in this document. No adjunctive oral screening devices, salivary tests, or imaging systems are described as covered in the text."

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