Homocysteine Testing

Aetna covers CPT 83090 (homocysteine) only for specific indications — assessment of borderline vitamin B12 deficiency when results will affect management, evaluation of central retinal vein occlusion with prior/family thrombosis or age <56 without strong arteriosclerotic risk factors, diagnosis of cystathionine β‑synthase homocystinuria (newborn testing only after confirmed hypermethioninemia), and assessment of idiopathic, recurrent, young‑onset (<45) or unusual‑site venous thromboembolism. Homocysteine testing is experimental/investigational and not covered for all other indications, including use as a biomarker for erectile dysfunction, gastric cancer, pre‑eclampsia, or carotid artery stenosis with coronary artery disease.

"U09."

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