CG-LAB-13 Skin Nerve Fiber Density Testing

This policy addresses pathological analysis of intra-epidermal nerve fiber density (via skin punch biopsy) for diagnosing small-fiber neuropathy. It is medically necessary only when the patient has painful sensory neuropathy and there is no evidence of large-fiber neuropathy on both physical examination and electromyography/nerve-conduction studies; in all other situations it is not covered. Pathological analysis of sweat gland nerve fiber density is not medically necessary for any indication.

"Pathological analysis of intra-epidermal nerve fiber density for the diagnosis of small-fiber neuropathy is consideredmedically necessarywhenbothof the following conditions are met:"

Sign up to see full coverage criteria, indications, and limitations.