Payer PolicyActive
LAB.00037 Serologic Testing for Biomarkers of Irritable Bowel Syndrome (IBS)
ANTHEM-LAB.00037
Anthem
Effective: January 30, 2025
Updated: December 30, 2025
Policy Summary
This policy addresses serologic testing for irritable bowel syndrome (IBS) biomarkers such as anti-CdtB and anti-vinculin, including ibs-smart and IBSchek. Anthem deems these tests investigational/experimental and not medically necessary; they are not covered for any use, including screening, diagnosis, or management of IBS. There are no covered indications or exceptions, regardless of test setting (venipuncture or home-based collection).
Coverage Criteria Preview
Key requirements from the full policy
"Serological testing for biomarkers of irritable bowel syndrome (for example, CdtB and anti-vinculin), is consideredinvestigational and not medically necessaryfor screening, diagnosis or management ..."
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