Payer PolicyActive
LAB.00048 Analysis of Urine Biomarkers for Chronic Pain Management
ANTHEM-LAB.00048
Anthem
Effective: July 1, 2025
Updated: December 30, 2025
Policy Summary
This policy addresses urine biomarker analysis for chronic pain management, including tests such as the Functional Pain Index (Pain Index Score). Anthem considers these services investigational/experimental and not medically necessary; they are not covered for any indication. Non-coverage applies regardless of clinical intent (for determining pain etiology, reducing opioid use, or guiding non-opioid therapy), with no exceptions or special circumstances.
Coverage Criteria Preview
Key requirements from the full policy
"Analysis of urine biomarkers to assess chronic pain is consideredinvestigational and not medically necessaryfor all indications."
Sign up to see full coverage criteria, indications, and limitations.