Payer PolicyActive
LAB.00051 Per- and Polyfluoroalkyl Substances (PFAS) Testing
ANTHEM-LAB.00051
Anthem
Effective: October 1, 2025
Updated: December 30, 2025
Policy Summary
This policy addresses laboratory testing to detect per- and polyfluoroalkyl substances (PFAS) in human specimens. PFAS testing is considered investigational and not medically necessary; therefore, it is not covered for any indication, including screening, diagnostic evaluation, exposure assessment, or monitoring. Non-coverage applies across all settings and methods (e.g., CPT 82542, 83921, 84999), with no exceptions or medical-necessity criteria.
Coverage Criteria Preview
Key requirements from the full policy
"Testing for PFAS substances is consideredinvestigational and not medically necessaryfor all indications."
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