Payer PolicyActive
MED.00151 Gene Therapy for Aromatic L-Amino Acid Decarboxylase Deficiency
ANTHEM-MED.00151
Anthem
Effective: October 1, 2025
Updated: December 30, 2025
Policy Summary
This policy addresses gene therapy for aromatic L‑amino acid decarboxylase (AADC) deficiency using eladocagene exuparvovec‑tneq. Anthem considers this therapy investigational/experimental and not medically necessary; therefore, it is not covered for any indication. There are no covered circumstances or exceptions under this policy, and related services (e.g., billed under 64999, C9399, J3490, J3590) are subject to denial.
Coverage Criteria Preview
Key requirements from the full policy
"Gene therapy for aromatic l-amino acid decarboxylase deficiency using eladocagene exuparvovec-tneq is consideredinvestigational and not medically necessaryfor all indications."
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