Payer PolicyActive
TRANS.00004 Cell Transplantation (Mesencephalic, Adrenal-Brain and Fetal Xenograft)
ANTHEM-MP-A053523
Anthem
Effective: April 16, 2025
Updated: December 30, 2025
Policy Summary
- Service: Implantation of adrenal tissue, fetal mesencephalic tissue, or fetal xenograft tissue into the brain for Parkinson’s disease or any other indication. - Coverage: Anthem considers these procedures investigational/experimental and not medically necessary; there are no covered indications (not covered for PD or any other condition). - Limitations: Applies across all settings; relevant billing codes include HCPCS/CPT 64999 and S2103, and ICD-10 codes G20.A1, G20.C, G21.0, G21.9.
Coverage Criteria Preview
Key requirements from the full policy
"Transplantation of adrenal, fetal mesencephalic and xenograft fetal tissues to the brain is consideredinvestigational and not medically necessaryfor the treatment of Parkinsonâs disease and for a..."
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