Payer PolicyActive
SURG.00165 Histotripsy
ANTHEM-SURG.00165
Anthem
Effective: October 21, 2025
Updated: December 30, 2025
Policy Summary
This policy addresses histotripsy, a non-thermal ultrasound ablation technique for destroying liver tumors. It is medically necessary only for primary or metastatic liver tumors when other treatments are not available or appropriate—evidenced by at least one of the following: unresponsive to prior therapies, relapse after prior therapies, intolerance to available therapies, or thermal ablation is not viable due to tumor location. All other uses, or when these criteria are not met, are considered investigational and not medically necessary.
Coverage Criteria Preview
Key requirements from the full policy
"Histotripsy is consideredmedically necessarywhenallof the following criteria (A, B, C, and D) are met:"
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