Payer PolicyActive
Repository corticotropin injection (Acthar)
EVICORE-MEDICAL_DRUG-132E8E71
EviCore by Evernorth
Effective: June 1, 2020
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Acthar Gel is covered only as monotherapy for FDA‑approved infantile spasms (West syndrome) in infants/children under 2 years; other FDA‑approved indications are not automatically covered and require medical director review. Approval requires documented diagnosis and age, prescription by or in consultation with a neurologist, a 1‑month authorization with dosing 150 U/m2 IM (75 U/m2 twice daily) and a taper after 2 weeks over 2 weeks, and meeting applicable safety criteria.
Coverage Criteria Preview
Key requirements from the full policy
"Acthar is prescribed by or in consultation with a neurologist (prescriber/consult requirement)."
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