Payer PolicyActive
Ranibizumab (Lucentis)
EVICORE-MEDICAL_DRUG-1B7F16B4
EviCore by Evernorth
Effective: November 1, 2020
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Lucentis (ranibizumab) is covered for FDA‑approved indications (neovascular/wet AMD, RVO‑related macular edema, DME, DR, mCNV) and select compendial neovascular ophthalmic uses; uses outside these are not supported. Approval is for up to 12 months, must be administered by or under an ophthalmologist, and requires documentation of diagnosis, indication‑specific intravitreal dosing/frequency (0.5 mg monthly for wet AMD/RVO, 0.3 mg monthly for DME/DR, 0.5 mg monthly for mCNV limited to 3 months) and treatment duration/rationale.
Coverage Criteria Preview
Key requirements from the full policy
"Macular edema following retinal vein occlusion (RVO)"
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