Payer PolicyActive
Syfovre (pegcetacoplan)
EVICORE-MEDICAL_DRUG-210E06E6
EviCore by Evernorth
Effective: January 1, 2024
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Syfovre is covered only for geographic atrophy secondary to age-related macular degeneration (not GA from other causes) and only for the FDA‑approved indication, with authorization limited to 12 months. Coverage requires BCVA of ≥24 ETDRS letters (~20/320) documented, administration by or under supervision of an ophthalmologist, documentation of diagnosis and treatment plan, and dosing of 15 mg intravitreal injections to each affected eye every 25–60 days.
Coverage Criteria Preview
Key requirements from the full policy
"Syfovre must be administered by or under the supervision of an ophthalmologist."
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