Payer PolicyActive
Pegaptanib Sodium (Macugen)
EVICORE-MEDICAL_DRUG-2FB17578
EviCore by Evernorth
Effective: December 1, 2019
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Pegaptanib (Macugen) is covered only for neovascular (wet) AMD and the specified compendial off‑label uses listed (diabetic retinopathy, neovascular glaucoma, retinopathy of prematurity, sickle cell neovascularization, and choroidal neovascular conditions); other uses are not covered. Coverage requires administration by or under an ophthalmologist, documented intravitreous dosing ≤0.3 mg every 6 weeks, documentation of the covered diagnosis and administration, and approvals (initial and renewals) for up to 12 months.
Coverage Criteria Preview
Key requirements from the full policy
"Neovascular (Wet) age-related macular degeneration (AMD) (FDA-approved indication)"
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