Repository corticotropin injection (Acthar)

Acthar Gel is covered only for FDA‑approved uses—infantile spasms in children <5 years and acute multiple sclerosis exacerbations in adults—and other indications are not covered. Approval is limited to 1 month and requires documented diagnosis, neurologist/epileptologist (or MS specialist) prescription or consult, a treatment plan with recommended dosing, and for MS evidence of inability to use high‑dose IV corticosteroids or a trial with a severe adverse effect (no routine monthly "pulse" use).

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