Payer PolicyActive
Avastin® (bevacizumab) Non-oncology
EVICORE-MEDICAL_DRUG-8629C644
EviCore by Evernorth
Effective: June 1, 2024
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Avastin (bevacizumab) is covered for non‑oncology compendial off‑label neovascular/vascular ophthalmic conditions (e.g., diabetic macular edema/retinopathy, RVO‑related macular edema, myopic choroidal neovascularization, neovascular AMD, and other ocular neovascular diseases); oncology indications are excluded. Coverage requires documented diagnosis of an approved off‑label compendial use, meeting specific coverage and safety criteria, administration by or under an ophthalmologist’s supervision, and is authorized for up to 12 months.
Coverage Criteria Preview
Key requirements from the full policy
"When requesting Avastin (bevacizumab) for non-oncology uses, the individual requiring treatment must be diagnosed with an approved off-label compendial use and meet the specific coverage guidelines..."
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