Payer PolicyActive
Ranibizumab (Lucentis®) Injection
EVICORE-MEDICAL_DRUG-A0653004
EviCore by Evernorth
Effective: October 1, 2021
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Lucentis (ranibizumab) is covered for FDA‑approved indications (neovascular/wet AMD, RVO‑related macular edema, DME, DR, mCNV) and certain compendial off‑label neovascular ophthalmic uses, with no explicit exclusions listed. Approval requires ophthalmologist administration/supervision, intravitreal dosing per indication (0.5 mg monthly for wet AMD/RVO, 0.3 mg monthly for DME/DR, 0.5 mg monthly for up to 3 doses for mCNV), and is authorized for up to 12 months.
Coverage Criteria Preview
Key requirements from the full policy
"Neovascular (wet) age-related macular degeneration (AMD)"
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