Payer PolicyActive
Ranibizumab (Lucentis)
EVICORE-MEDICAL_DRUG-D037D452
EviCore by Evernorth
Effective: December 1, 2018
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Lucentis (ranibizumab) is covered only for the listed FDA‑approved ocular indications (neovascular AMD; RVO‑related macular edema; DME; DR with DME; mCNV) and excluded for non‑FDA‑approved/off‑label uses, and coverage is conditional on absence of ocular/periocular infection and absence of active intraocular inflammation. Authorization requires documentation of the diagnosis, documentation that infection/inflammation are absent, a planned dosing regimen of 0.3 mg intravitreal approximately every 28 days, and supports up to 12 months of approval.
Coverage Criteria Preview
Key requirements from the full policy
"Neovascular (wet) age-related macular degeneration (AMD)"
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