Payer PolicyActive
Vpriv® (velaglucerase alfa)
EVICORE-MEDICAL_DRUG-F238EE9F
EviCore by Evernorth
Effective: June 1, 2023
Updated: January 13, 2026
created · Dec 4, 2025
Policy Summary
Vpriv (velaglucerase alfa) is covered only for FDA‑approved treatment of Type 1 Gaucher disease and is not supported for other diagnoses or Gaucher types. Coverage requires documented diagnosis (deficient β‑glucocerebrosidase activity in leukocytes/fibroblasts or molecular GBA mutation), prescription by or documented consultation with a geneticist, endocrinologist, metabolic disorder or lysosomal storage disorder specialist, dosing 60 U/kg IV no more frequently than every 2 weeks, and approval is limited to one year.
Coverage Criteria Preview
Key requirements from the full policy
"Approval duration limited to 1 year."
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