Payer PolicyActive
CMM-204: Prolotherapy
EVICORE-MSK_ADVANCED-6267F5BE
EviCore by Evernorth
Effective: October 22, 2018
Updated: January 13, 2026
created · Dec 5, 2025
Policy Summary
Prolotherapy (CPT/HCPCS M0076) is considered experimental, investigational, or unproven for treatment of musculoskeletal pain and/or instability (e.g., laxity, weakness) and is thus not covered. No specific documentation requirements or covered indications are provided, and final reimbursement determinations rest with the individual health plan.
Coverage Criteria Preview
Key requirements from the full policy
"Based on the lack of conclusive scientific evidence demonstrating the clinical efficacy of prolotherapy combined with the potential to expose individuals to adverse side effects or complications, t..."
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